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Home > Products > PEG Derivatives> (NHS) PEGs> NHS-PEG-NHS ,MW:750
NHS-PEG-NHS ,MW:750
Catalog # Pkg Size Price Quantity Shopping Cart
R-200207 1g ¥ 1550
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R-200207 5g ¥ 5500
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结构式
外观 白色粉末/固体
分子量 750
溶解度 氯仿、甲醇、DMSO
CAS号 N/A
质量控制 95%
储存条件 -20℃
保存时间 1年
其他信息 N/A
N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH2) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.
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